Alzheimer's Disease

Patient complaint: Dementia.

MR has been chosen for the above images because of its ability to show greater detail in Alzheimer's disease.
The image on the above is a thin-section coronal T1-weighted MRI of an individual with Alzheimer's.
The arrows indicate focal, assymetric atrophy of the right medial temporal lobe.
Also visible on the above are the dilated lateral and third ventricles most likely due to diffuse atrophy.
The down image is an age-matched control for comparison.

Both images above are SPECT images using Tc-99 in an individual with severe Alzheimer's disease.
The image on the above is taken as if looking at the patient's left hemisphere, and vice versa for the image on the below.
The arrows indicate bilateral frontal, temporal, and parietal hypoperfusion as seen by areas of hypodensity.
FL = frontal lobe; TL = temporal lobe; PL = parietal lobe